Xiang, Wenlong team published research in Chemical Engineering Science in 2021 | 10111-08-7

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Related Products of 10111-08-7

Imidazole based anticancer drug find applications in cancer chemotherapy. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). Related Products of 10111-08-7.

Xiang, Wenlong;Shen, Chenyang;Lu, Zhe;Chen, Si;Li, Xiang;Zou, Rui;Zhang, Yueping;Liu, Chang-jun research published 《 CO2 cycloaddition over ionic liquid immobilized hybrid zeolitic imidazolate frameworks: Effect of Lewis acid/base sites》, the research content is summarized as follows. Ionic liquid (IL) immobilized zeolitic imidazolate framework (ZIF) catalysts (IL-ZIF-8) were prepared through grafting IL on a dual-ligand ZIF by a facile post-synthetic modification. The coordinately unsaturated Zn as Lewis acid sites and bromide ions as Lewis base sites were confirmed in the resulted IL-ZIF. The d. of Lewis acid/base sites was tuned easily by content of mixed linkers in the framework and/or the IL loadings. The coexistence of Lewis acid/base sites remarkably improved the activity for cycloaddition of CO2 with propylene oxide, compared with parent ZIFs and IL. In the absence of any co-catalyst and solvent, the prepared IL-ZIF-8(0.3) obtained a high yield of 97% with good stability and reusability. Besides, a Lewis acid/base synergistic catalytic mechanism was proposed. The synergetic interaction of Lewis acid sites and Lewis base sites significantly reduces energy barrier of propylene oxide ring-opening to 11.5 kcal mol-1 and thus promotes the CO2 cycloaddition reaction.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Related Products of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem