Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Computed Properties of 10111-08-7.
Skrodzki, Maciej;Ortega Garrido, Victor;Csaky, Aurelio G.;Pawluc, Piotr research published 《 Searching for highly active cobalt catalysts bearing Schiff base ligands for Markovnikov-selective hydrosilylation of alkynes with tertiary silanes》, the research content is summarized as follows. The search for simple and easy-to-synthesize ligands for bench stable cobalt (pre)catalysts that would ensure high activity and selectivity in alkyne hydrosilylation reactions is an interesting current challenge. Herein, we report that a cobalt(II) complex bearing pyrimidine-imine-2H-imidazole ligand activated by LiHBEt3 exhibits not only high catalytic activity, but also unprecedented tolerance towards tertiary silanes in highly regioselective Markovnikov hydrosilylation of aliphatic and aromatic terminal alkynes to give α-vinylsilanes. In addition, a variety of 1-aryl-2-(trimethylsilyl)acetylenes have been hydrosilylated efficiently by diphenylsilane in the presence of [Co(L)Cl2]/LiHBEt3 catalytic system to yield (E)-1-aryl-1,2-bis(silyl)ethenes with high selectivity. Such selectivity is very rarely observed for cobalt-catalyzed hydrosilylation of silylacetylenes.
Computed Properties of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem