Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 250285-32-6, formula is C27H37ClN2, Name is 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Recommanded Product: 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride.
Segato, Jacopo;Del Zotto, Alessandro;Belpassi, Leonardo;Belanzoni, Paola;Zuccaccia, Daniele research published 《 Hydration of alkynes catalyzed by [Au(X)(L)(ppy)]X in the green solvent γ-valerolactone under acid-free conditions: the importance of the pre-equilibrium step》, the research content is summarized as follows. [AuCl(NHC)(ppy)]Cl and [AuCl(PPh3)(ppy)]OTf complexes [ppy = 2-phenylpyridine, NHC = 1,3-bis(2,6-di-isopropylphenyl)-imidazol-2-ylidene] successfully catalyze the hydration of alkynes in γ-valerolactone (GVL), under acid-free conditions. The solution structure, reactivity, and catalytic properties of [AuCl(NHC)(ppy)]Cl and [AuCl(PPh3)(ppy)]OTf were established by means of multinuclear NMR and computational (DFT) studies. Structural features of [AuCl(NHC)(ppy)]Cl during the catalysis, inferred by NMR spectroscopy, clearly indicate that complex [AuCl(NHC)(ppy)]Cl retains its square planar structure and no reduction to Au(I) and/or Au(0) nanoparticles was observed The overall catalytic and kinetic investigations [kinetic isotopic effect (KIE), effect of acid additives, the order of reaction with respect to the catalyst, alkyne and nucleophile and the effect of the temperature] supported by computational results confirm that the pre-equilibrium step of the reaction mechanism is the RDS: water or counterion substitution by 3-hexyne in the first co-ordination sphere of Au(III) is the key step of the whole process. The description of the mechanism of the hydration of 3-hexyne catalyzed by [AuCl(NHC)(ppy)]Cl here reported appears therefore to be of high significance because comprehensive mechanistic studies of the Au(III)-catalyzed hydration reaction of the CC bond are scarce in the literature and generally lack exptl. basis.
250285-32-6, 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride, also known as 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride, is a useful research compound. Its molecular formula is C27H37ClN2 and its molecular weight is 425 g/mol. The purity is usually 95%.
1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride has been used to generate N-heterocyclic carbene catalysts for use in carbonylative cross-coupling of pyridyl halides with aryl boronic acids.
1,3-Bis(2,6-diisopropylphenyl)imidazolium Chloride is an imidazolium salt that is active against all stages of Trypanosoma cruzi and may represent a promising candidate for treatment of Chagas disease.
1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride is an organic compound that is used as a solvent. It was originally synthesized by reacting triethyl orthoformate with 2,6-diisopropylaniline. This reaction formed the corresponding imidazolium salt. The synthesis of this compound was later improved by using ring-opening polymerization of glycolide and furfural. 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride is mainly used to extract estradiol from urine samples in clinical laboratories., Recommanded Product: 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem