Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. It is also known as 1, 3-diazole. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen. Application In Synthesis of 1739-84-0.
Ramezanzadeh, Forough;Mamaghani, Manouchehr;Fallah-Bagher Shaidaei, Hossein;Sheykhan, Mehdi research published 《 Synthesis and Application of Imidazolium-Based Ionic Liquid Supported on Hydroxyapatite Encapsulated γ-Fe2O3 Nanocatalyst in Preparation of Pyrido[2,3-d]Pyrimidines》, the research content is summarized as follows. Synthesis of novel 2-amino-5-aryl-7-(1-methyl-1H-pyrrol-2-yl)-4-oxo-3,4,5,8-tetrahydro-pyrido[2,3-d]pyrimidine-6-carbonitrile derivatives I (Ar = 4-chlorophenyl, thiophen-2-yl, naphthalen-1-yl) is reported by the reaction of 2,6-diaminopyrimidin-4(3H)-one, 3-(1-methy-1H-pyrrol-2-yl)-3-oxopropane nitrile and aryl aldehydes ArCHO in the presence of newly synthesized imidazolium based ionic liquid supported on hydroxyapatite encapsulated γ-Fe2O3 nanocatalyst [γ-Fe2O3@HAp-Si(CH2)3Cl@DMIM] in short reaction times (7-13 min) and high to excellent yields (80%-95%). Cleaner reaction profile, mild reaction conditions, use of the green solvent, and reusability of the catalyst make this protocol attractive for the large scale synthesis of pyrido[2,3-d]pyrimidine-6-carbonitrile derivatives I and are amenable for iterative combinatorial library generation. The synthesized nanoparticles were characterized by Fourier transform IR spectroscopy, X-ray diffraction, scanning electron microscope, energy dispersive anal. of X-rays, thermogravimetric anal., differential thermogravimetric and vibrating sample magnetometer.
Application In Synthesis of 1739-84-0, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem