Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Name: 1H-Imidazole-2-carbaldehyde.
Rafiee, Fatemeh;Shirzadi, Faezeh research published 《 The synthesis and characterization of a magnetic histidine Schiff base palladium complex and its efficiency investigation in the nitroarene pollutants reduction and dyes degradation》, the research content is summarized as follows. At first, we prepared the chloropropyl-modified Fe3O4@SiO2 nanoparticles and functionalized it with imidazole-2carbaldehyde to provide an aldehyde functional group for the Schiff base formation with histidine amino acid. The nitrogen atoms of imidazole cycles, -C=N bonds, and -COOH groups of histidine could act as proper coordination positions for palladium complex formation. The obtained magnetic histidine Schiff base palladium complex (Fe3O4@SiO2@Im-His@Pd) was characterized by fourier transform IR (FT-IR), field-emission SEM (FE-SEM), energy dispersive X-ray (EDX), X-ray diffraction (XRD), vibrating sample magnetometer (VSM) and inductively coupled plasma-optical emission spectrometry (ICP-OES) anal. The prepared nanocomposite has shown good efficiency in the reduction of nitroarenes and dyes degradation under mild conditions at room temperature in short reaction times.
Name: 1H-Imidazole-2-carbaldehyde, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem