Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Reference of 10111-08-7.
Pan, Yong;Xie, Rui;Xu, BaoMing;Chen, Chi research published 《 Determination of sorption and diffusion for ethanol through superhydrophobic ZIF/PDMS mixed matrix membrane》, the research content is summarized as follows. The hydrophobicity-hydrophilicity properties of the surface play decisive roles in the resultant separation performance of the membrane, especially the hydrophobicity of mixed matrix membranes (MMMs) for pervaporation recovery of various organic systems from aqueous solution Herein, superhydrophobic Zeolitic Imidazolate Framework-90 (S-ZIF-90) was employed as filler to incorporate into Polydimethylsiloxane (PDMS) to prepare superhydrophobic S-ZIF-90/PDMS MMMs for ethanol permselective pervaporation. The chem. structures and superhydrophobicity properties of the surface of S-ZIF-90 and S-ZIF-90/PDMS MMMs were demonstrated by various characterization techniques. The results showed that S-ZIF-90 particles and S-ZIF-90/PDMS composite membranes were successfully prepared and S-ZIF-90/PDMS MMMs have higher hydrophobicity property as compared to ZIF-90/PDMS MMMs or pure PDMS. Therefore, S-ZIF-90/PDMS MMMs showed more excellent separation performance than ZIF-90/PDMS MMMs or pure PDMS. In particular, S-ZIF-90/PDMS MMMs with 15 wt% S-ZIF-90 loading have a total flux of 1064 g/(m2 h) with a maximum separation factor of 14.9 at 40°C for 5 wt% dilute ethanol solution The diffusion coefficients, permeation coefficients, adsorption heat and adsorption entropy of ethanol and water were also calculated by sorption tests, which might provide a method to further determinate the mass transfer mechanism of MMMs in pervaporation process.
10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Reference of 10111-08-7
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem