Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Electric Literature of 10111-08-7.
Mollick, Samraj;Saurabh, Satyam;More, Yogeshwar D.;Fajal, Sahel;Shirolkar, Mandar M.;Mandal, Writakshi;Ghosh, Sujit K. research published 《 Benchmark uranium extraction from seawater using an ionic macroporous metal-organic framework》, the research content is summarized as follows. Large-scale uranium extraction from seawater (UES) is widely considered as reconciliation to increasing global energy demand and climate change crises. However, an ideal uranium sorbent combining the features of high capacity, excellent selectivity, and ultra-fast kinetics is highly desirable but a long-standing challenge due to the lack of a proper adsorbent. Herein, we adopted a prototypal hybridization strategy to design a rare ionic macroporous metal-organic framework (MOF) decorated with multiple functional groups. The resulting ionic adsorbent captures 99.98% of the uranium in just 120 min (from ∼50 000 to ∼10 ppb) and offers a very large distribution coefficient, KUd > 107 mL g-1, demonstrating a strong affinity towards uranium. Notably, the material harvests 96.3% of uranium simply in 120 min from natural seawater, affording a remarkable enrichment index of 25044 and thereby introducing a new benchmark uranium adsorbent. Moreover, it satisfied the preset target of the UES standard (6 mg g-1) within 2 days and achieved a record uranium uptake capacity of 28.2 mg g-1 from natural seawater only in 25 days, which is a significant breakthrough in UES. The structural evidence from both exptl. and theor. studies confirmed that the formation of favorable chelating motifs into the ionic macropores governs the highly selective recovery of uranium from water.
Electric Literature of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem