On July 31, 1992, Seela, Frank; Gumbiowski, Rainer published an article.Category: imidazoles-derivatives The title of the article was Imidazo[1,2-a]pyrimidine 2′-deoxyribo- and 2′,3′-dideoxyribonucleosides: glycosylation of the nucleobase anion. And the article contained the following:
The synthesis of the imidazopyrimidine deoxyribonucleosides I (R = NH2, H, R1 = H, R2 = H, OH) via stereoselective glycosidation of the nucleobase anion of II, is described. The inhibitory activity of the dideoxynucleoside 5′-triphosphates I (R = H, NH2, R1 = P3O9H4, R2 = H) against HIV reverse transcriptase was tested. The experimental process involved the reaction of 7-Chloroimidazo[1,2-a]pyrimidin-5(1H)-one(cas: 57473-33-3).Category: imidazoles-derivatives
The Article related to imidazopyrimidine deoxyribonucleoside preparation phosphorylation, nucleotide dideoxy imidazopyrimidine triphosphate enzyme inhibition, nucleoside deoxy imidazopyrimidine preparation phosphorylation, stereoselective glycosidation chloroimidazopyrimidinone and other aspects.Category: imidazoles-derivatives
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem