Boix, C.; Ibanez, M.; Sancho, J. V.; Niessen, W. M. A.; Hernandez, F. published an article in 2013, the title of the article was Investigating the presence of omeprazole in waters by liquid chromatography coupled to low and high resolution mass spectrometry: degradation experiments.Reference of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole And the article contains the following content:
Omeprazole is one of the most consumed pharmaceuticals around the world. However, this compound is scarcely detected in urban wastewater and surface water. The absence of this pharmaceutical in the aquatic ecosystem might be due to its degradation in wastewater treatment plants, as well as in receiving water. Different laboratory-controlled degradation experiments were carried out on surface water to elucidate omeprazole transformation products (TPs). Surface water spiked with omeprazole was subjected to hydrolysis, photo-degradation under both sunlight and UV radiation and chlorination. Analyses by liquid chromatog. coupled to quadrupole time-of-flight mass spectrometry (LC-QTOF MS) permitted identification of ≤17 omeprazole TPs. In a subsequent step, the TPs identified were sought in surface water and urban wastewater by LC-QTOF MS and by LC coupled to tandem mass spectrometry with triple quadrupole. The parent omeprazole was not detected in any of the samples, but 4 TPs were found in several water samples. The most frequently detected compound was OTP 5 (omeprazole sulfide), which might be a reasonable candidate to be included in monitoring programs rather than the parent omeprazole. Copyright pr 2013 John Wiley & Sons, Ltd. The experimental process involved the reaction of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole(cas: 73590-85-9).Reference of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole
The Article related to omeprazole water liquid chromatog mass spectrometry degradation, omeprazole, surface water, time-of-flight mass spectrometry, transformation/degradation products, triple quadrupole mass spectrometry, ultra-high-performance liquid chromatography, urban wastewater and other aspects.Reference of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole
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Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem