In 2022,Wang, Pengzhi; Fitzpatrick, Keegan P.; Scheidt, Karl A. published an article in Advanced Synthesis & Catalysis. The title of the article was 《Combined Photoredox and Carbene Catalysis for the Synthesis of γ-Aryloxy Ketones》.Product Details of 530-62-1 The author mentioned the following in the article:
N-heterocyclic carbenes (NHCs) have emerged as catalysts for the construction of C-C bonds in the synthesis of substituted ketones under single-electron processes. Despite these recent reports, there still remains a need to increase the utility and practicality of these reactions by exploring new radical coupling partners. Herein, authors report the synthesis of γ-aryloxyketones via combined NHC/photoredox catalysis. In this reaction, an α-aryloxymethyl radical is generated via oxidation of an aryloxymethyl potassium trifluoroborate salt, which is then added into styrene derivatives to provide a stabilized benzylic radical. Subsequent radical-radical coupling reaction with an azolium radical affords the γ-aryloxy ketone products.Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Product Details of 530-62-1) was used in this study.
Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Product Details of 530-62-1
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem