Recommanded Product: 1H-Benzo[d]imidazol-2-amineIn 2021 ,《Characterization of a novel carbendazim-degrading strain Rhodococcus sp. CX-1 revealed by genome and transcriptome analyses》 was published in Science of the Total Environment. The article was written by Long, Zhengnan; Wang, Xiuguo; Wang, Yingjun; Dai, Huawei; Li, Changhao; Xue, Yongfei; Deng, Yanfei; Zhang, Houpu; Yu, Yunlong; Fang, Hua. The article contains the following contents:
The persistence and ecotoxicity of carbendazim residues pose a potential risk to environmental ecol. and human health. Here, a novel and highly efficient carbendazim-degrading bacterium Rhodococcus sp. CX-1, capable of utilizing carbendazim as its sole source of carbon and energy, was isolated from contaminated soil. The biodegradation characteristics and metabolic pathways were studied by mass spectrometry, genomic annotation, and transcriptome anal. The degradation rate of carbendazim by strain CX-1 was 3.98-9.90 mg/L/h under different conditions, and the optimum degradation conditions were 40°C and pH 7.0. The addition of carbon sources (glucose, fructose, and sucrose, 100 mg/L) could accelerate carbendazim degradation HPLC-MS/MS identification suggested that carbendazim is first hydrolyzed into 2-aminobenzimidazole and then to 2-hydroxybenzimidazole, and is ultimately mineralized to carbon dioxide. The genome of strain CX-1 contained 6,511,628 bp nucleotides, 2 linear plasmids, 2 circular plasmids, and 6437 protein coding genes. Genome annotation and transcriptome anal. indicated that carbendazim degradation may be regulated by the degradation genes harbored in the chromosome and in plasmid 2, and two different degradation pathways of carbendazim by imidazole ring cleavage or benzene ring cleavage were predicted. This study provided new insight to reveal the biodegradation mechanism of carbendazim; furthermore, strain CX-1 is a promising bioresource for carbendazim bioremediation. In the experimental materials used by the author, we found 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Recommanded Product: 1H-Benzo[d]imidazol-2-amine)
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Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem