Hermanns, Volker; Scheurer, Maximilian; Kersten, Nils Frederik; Abdellaoui, Chahinez; Wachtveitl, Josef; Dreuw, Andreas; Heckel, Alexander published their research in Chemistry – A European Journal in 2021. The article was titled 《Rethinking Uncaging: A New Antiaromatic Photocage Driven by a Gain of Resonance Energy》.Recommanded Product: 530-62-1 The article contains the following contents:
Photoactivatable compounds for example photoswitches or photolabile protecting groups (PPGs, photocages) for spatiotemporal light control, play a crucial role in different areas of research. For each application, parameters such as the absorption spectrum, solubility in the resp. media and/or photochem. quantum yields for several competing processes need to be optimized. The design of new photochem. tools therefore remains an important task. In this study, we exploited the concept of excited-state-aromaticity, first described by N. Colin Baird in 1971, to investigate a new class of photocages, based on cyclic, ground-state-antiarom. systems. Several thio- and nitrogen-functionalized compounds were synthesized, photochem. characterized and further optimized, supported by quantum chem. calculations After choosing the optimal scaffold, which shows an excellent uncaging quantum yield of 28 %, we achieved a bathochromic shift of over 100 nm, resulting in a robust, well accessible, visible light absorbing, compact new photocage with a clean photoreaction and a high quantum product (ε·Φ) of 893 M-1 cm-1 at 405 nm. The results came from multiple reactions, including the reaction of Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Recommanded Product: 530-62-1)
Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Recommanded Product: 530-62-1
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem