《Some studies in sulfadiazine incorporating pyridine, pyrimidine, oxadiazole, and azo moieties endowed with pharmaceutical potency》 was published in Acta Chimica Slovenica in 2020. These research results belong to El-Hadidya, Sherihan A.; Abu-Melhab, Sraa. Computed Properties of C3H5N3 The article mentions the following:
A set of substituted sulfadiazine compounds was prepared as cytotoxic and antitumor agents by using 4-amino-N-(pyrimidin-2-yl)benzenesulfonamide (1) as the starting material. Compound 1 was reacted with different reagents to give the corresponding sulfadiazines 2-18 and hydrozaones 19a-h which were evaluated for their in vitro cytotoxicity vs. four cancer cell lines. Compounds 3, 5, 19d and 19h were active against the tested cancer cells. The experimental process involved the reaction of 1H-Imidazol-2-amine(cas: 7720-39-0Computed Properties of C3H5N3)
1H-Imidazol-2-amine(cas: 7720-39-0) belongs to anime. Milder oxidation, using reagents such as NaOCl, can remove four hydrogen atoms from primary amines of the type RCH2NH2 to form nitriles (R―C≡N), and oxidation with reagents such as MnO2 can remove two hydrogen atoms from secondary amines (R2CH―NHR′) to form imines (R2C=NR′). Tertiary amines can be oxidized to enamines (R2C=CHNR2) by a variety of reagents.Computed Properties of C3H5N3
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem