The author of 《Methanesulfonylation of 2-benzimidazolemethanol and α-(2-benzimidazolyl)benzyl alcohol》 were Charlson, Alexander J.. And the article was published in Carbohydrate Research in 1973. Computed Properties of C10H12N2O The author mentioned the following in the article:
Treatment of 2-benzimidazolemethanol (I) with MeSO2Cl and pyridine in CHCl3 afforded 2-(chloromethyl)-1-(methylsulfonyl)benzimidazole (II), which was also prepared by methylsulfonylation of 2-(chloromethyl)benzimidazole. Methylsulfonylation of α-(2-benzimidazolyl)benzyl alc. (III) in CHCl3 yielded 2-(α-chlorobenzyl)-1-(methylsulfonyl)benzimidazole. 1-(Methylsulfonyl)-2-benzimidazolemethanol was obtained on methylsulfonylation of I in pyridine at 0°, and α-[1-(methylsulfonyl)-2-benzimidazolyl]benzyl alc. (IV) was prepared from III by using the same reaction conditions. The reaction of 1-acetyl-2-(chloromethyl)benzimidazole with MeSO3Ag in benzene gave 1-acetyl-O-(methylsulfonyl)-2-benzimidazolemethanol. II has some antitumor activity in the KB cell-culture system, and some antibacterial activity in the Staphylococcus aureus test-system; it is also active in preventing anaphylactic shock in a mouse test-system.3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol(cas: 2403-66-9Computed Properties of C10H12N2O) was used in this study.
3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol(cas: 2403-66-9) belongs to imidazoles.Imidazole rings are part of unnatural cyclic peptides and are used as ester isosteres in peptidomimetic studies.
However, the application of imidazoles is not limited to the field of peptides and peptidomimetics. Computed Properties of C10H12N2O
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem