Ambati, Srinivasa Rao; Patel, Jeevan Lal; Chandrakar, Komal; Sarkar, Uttam; Penta, Santhosh; Banerjee, Subhash; Varma, Rajender S. published the artcile< One-pot, three-component synthesis of novel coumarinyl-pyrazolo[3,4-b]pyridine-3-carboxylate derivatives using [AcMIm]FeCl4 as recyclable catalyst>, Application of C6H9ClN2O2, the main research area is benzylhydrazine cyano hydroxyacrylate coumarinyl acrylaldehyde ionic liquid multicomponent reaction; benzyl coumarinyl pyrazolopyridine carboxylate preparation green chem.
Multicomponent synthesis of novel coumarin-based fused pyrazolo[3,4-b]pyridine-3-carboxylate derivatives I [R = H, OH, F, CN; R1 = Me, Et, i-Pr, t-Bu; R2 = H, MeO, Br] was developed using acidic ionic liquid, 1-acyl-3-methylimidazolium tetrachloroferrate ([AcMIm]FeCl4) under mild and environmentally benign reaction conditions. The prepared [AcMIm]FeCl4 served as a catalyst as well as the reaction medium and was reused for at least four times without significant loss of yield. The ensuing compounds, I were identified by FT-IR, 1H NMR and 13C NMR and mass spectroscopic studies. The developed method offers several advantages such as a simple protocol, excellent yields of the products (90-92%), shorter reaction time (2 h), recyclability of the catalyst, eco-friendly reaction conditions and better values of green chem. metrics like low E factor (0.32), high reaction mass efficiency (75.28%), low process mass efficiency (1.32) and high atom economy (81.82).
Journal of Molecular Structure published new progress about Aliphatic acids, esters Role: SPN (Synthetic Preparation), PREP (Preparation). 700370-07-6 belongs to class imidazoles-derivatives, and the molecular formula is C6H9ClN2O2, Application of C6H9ClN2O2.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem