《Development of a multistep, electrochemical flow platform for automated catalyst screening》 was written by Schotten, Christiane; Manson, Jamie; Chamberlain, Thomas W.; Bourne, Richard A.; Nguyen, Bao N.; Kapur, Nik; Willans, Charlotte E.. COA of Formula: C21H25ClN2This research focused ontriazole electrochem catalyst copper electrode. The article conveys some information:
The development of an integrated multistep flow platform that incorporates high-throughput electrochem. synthesis of metal catalysts and catalysis screening is described. Ligand libraries can be screened through the implementation of an autosampler, and online HPLC anal. facilitates continuous monitoring of the reaction. The equipment is controlled via a computer which enables the process to be automated, with the platform running ligand/catalysis screens autonomously. The platform has been validated using a ubiquitous Cu-NHC catalyzed click reaction, with conditions chosen so that the reaction does not run at full conversion, which allows the effect of different ligand precursors to be observed An efficient cleaning step is crucial to the reproducibility of reactions, and alternating polarity ensures the long-term stability of the electrochem. reactor. This technol. will enable the profiling of catalysts in continuous systems and accelerate the process of developing more sustainable base-metal catalysts in manufacturing processes. The experimental process involved the reaction of 1,3-Dimesityl-1H-imidazol-3-ium chloride(cas: 141556-45-8COA of Formula: C21H25ClN2)
1,3-Dimesityl-1H-imidazol-3-ium chloride(cas: 141556-45-8) is a ligand for arylation of aldehydes and for carbene catalyzed intermolecular arylation of C-H bonds. It is used as a phosphine-free ligand in various metal-catalyzed coupling reactions, often with advantageous results in difficult cases.COA of Formula: C21H25ClN2
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem