Category: imidazoles-derivativesIn 2019 ,《Green, effective and chromatography free synthesis of benzoimidazo[1,2-a]pyrimidine and tetrahydrobenzo [4,5]imidazo [1,2-d]quinazolin-1(2H)-one and their pyrazolyl moiety using Fe3O4@SiO2@L-proline reusable catalyst in aqueous media》 appeared in Journal of Organometallic Chemistry. The author of the article were Fekri, Leila Zare; Nikpassand, Mohammad; Khakshoor, Samira Nazari. The article conveys some information:
L-proline-functionalized silica-coated Fe3O4 nanoparticle was synthesized and characterized using Fourier Transform IR spectroscopy, X-ray diffraction, field emission SEM, transmission electron microscopy, energy dispersive X-ray spectroscopy, thermogravimetric anal., Zeta potential and a vibrating sample magnetometer. The Fe3O4@SiO2@L-proline nanoparticles in aqueous media were used as a green avenue for the mild and efficient multicomponent synthesis of new derivatives of benzoimidazo[1,2-a]pyrimidines and tetrahydrobenzo[4,5]imidazo-[1,2-d]quinazolin-1(2H)-ones in excellent yields. Furthermore, the recovery and reuse of the catalyst was demonstrated 10 times without a detectable loss in activity. Eco-friendliness, high purity of the desired products, short reaction time and easy workup was mentioned as the other advantages of this method. The results came from multiple reactions, including the reaction of 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Category: imidazoles-derivatives)
1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Category: imidazoles-derivatives
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem