Holden, Kenneth G.; Mattson, Matthew N.; Cha, Kyung Hoi; Rapoport, Henry published the artcile< Synthesis of Chiral Pilocarpine Analogues via a C-8 Ketone Intermediate>, Name: 5-Bromo-1-methyl-1H-imidazole, the main research area is pilocarpine analog chiral synthesis; oxazolidinone analog pilocarpine stereoselective synthesis.
The synthesis of a chiral pilocarpine analog I in which the lactone ring is replaced by an oxazolidinone and the bridging methylene group is in the ketone oxidation state has been accomplished. The utility of this compound as a key intermediate for the preparation of more complex structures was demonstrated by its reduction to two alc. epimers and its reaction with a methylene ylide.
Journal of Organic Chemistry published new progress about Alkaloids Role: SPN (Synthetic Preparation), PREP (Preparation) (imidazole-containing, oxazolidine analogs). 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Name: 5-Bromo-1-methyl-1H-imidazole.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem