In 2019,Analytical and Bioanalytical Chemistry Research included an article by Rajamohana, R.; Nayakib, S. Kothai; Swaminathanc, M.; Sivakumard, K.. Safety of 1H-Benzo[d]imidazol-2-amine. The article was titled 《pH independent complexation of 2-aminobenzimidazole with β-cyclodextrin》. The information in the text is summarized as follows:
The spectral characteristics of 2-aminobenzimidazole (2ABZ) in aqueous and ss-cyclodextrin media has been investigated using absorption, steady state and time resolved fluorescence techniques. The stoichiometric ratio of the inclusion complex of neutral and monocationic forms of 2ABZ in β-CDx medium is found to be 1:1. There is no significant differences between ground and the excited state pKa values of 2ABZ under both the media and thus the amino group of 2ABZ mol. is not much affected by the complexation process i.e., it lies outside the β-CDx cavity. Considering the shape and dimensions of β-CDx, it is clear that the 2ABZ mol. cannot be completely included in the β-CDx cavity. Because, the overall height of 2ABZ is 10.6 Å, but the overall height of β-CDx is only 7.8 Å. Hence, it is possible to locate half of the 2ABZ mol. only permitted inside the β-CDx cavity as interpreted using exptl. data. In the experiment, the researchers used 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Safety of 1H-Benzo[d]imidazol-2-amine)
1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Safety of 1H-Benzo[d]imidazol-2-amine
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem