Related Products of 3584-66-5On September 30, 2014 ,《Molecular properties prediction and synthesis of new benzimidazole H4-receptor antagonists as anti-inflammatory agents》 was published in Indian Journal of Heterocyclic Chemistry. The article was written by Bai, S. Anuradha; Tangeda, Sarita Jyostna; Madhavi, M.; Garlapati, Achaiah. The article contains the following contents:
The design and calculation of mol. properties, drug likeness, lipophilicity and solubility parameters of substituted benzimidazolyl carbonyl piperazines/piperidines I (R1 = Cl, CH3; R2 = H, Cl; R3 = CH3, C2H5; X = N, CH2) using mol inspiration, mol soft, software’s and ALOPGPS 2.1 program were investigated. Toxicity parameters were calculated using Osiris software. All compounds were non toxic; fulfill the solubility requirements and passing oral bioavailability criteria. Most of the compounds exhibited significant anti-inflammatory activity. In addition to this study using 5-Chloro-2-(trichloromethyl)-1H-benzo[d]imidazole, there are many other studies that have used 5-Chloro-2-(trichloromethyl)-1H-benzo[d]imidazole(cas: 3584-66-5Related Products of 3584-66-5) was used in this study.
5-Chloro-2-(trichloromethyl)-1H-benzo[d]imidazole(cas: 3584-66-5) belongs to imidazoles.Although other azole heterocycles are ubiquitous in a wide range of biologically active natural products, imidazole rings occur predominantly in the natural amino acid histidine. In addition, imidazole rings are part of unnatural cyclic peptides and are used as ester isosteres in peptidomimetic studies. Related Products of 3584-66-5
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem