In 2011,Abul Hashem, Md.; Sultana, Abeda published 《Synthesis of N-(2′-imidazolyl)-2-aminopyridyl palladium dichloride and its application as catalyst in Suzuki-Miyaura cross coupling reaction》.Journal of the Bangladesh Chemical Society published the findings.Synthetic Route of C3H3BrN2 The information in the text is summarized as follows:
The ligand N-(2′-imidazolyl)-2-aminopyridine was prepared from imidazole and it forms N-(2′-imidazolyl)-2-aminopyridyl palladium dichloride complex with Na2PdCl4 in methanol. The complex (1.5 mmol %) was used to prepare substituted biphenyls, terphenyls, and heterobiaryls in good to excellent yields via Suzuki-Miyaura cross-coupling reaction of substituted phenylboronic acids and substituted aryl chlorides, bromides and iodides. The experimental part of the paper was very detailed, including the reaction process of 2-Bromo-1H-imidazole(cas: 16681-56-4Synthetic Route of C3H3BrN2)
2-Bromo-1H-imidazole(cas: 16681-56-4) is a member of imidazole. Its exclusive structural characteristics with enviable electron-rich features are favorable for imidazole-based fused heterocycles to bind efficiently with an array of enzymes and receptors in biological systems through various weak interactions like hydrogen bonds, ion-dipole, cation-π, π-π stacking, coordination, Van der Waals forces, hydrophobic effects, etc., and therefore they demonstrate widespread bioactivities. Synthetic Route of C3H3BrN2
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem