《An AIE-active probe for selective fluorometric-colorimetric detection of HSO3- in aqueous solution and real samples》 was written by Han, Jia Hong; Gao, Wen Ying; Feng, Li Heng; Wang, Yu; Shuang, Shao Min. COA of Formula: C7H7N3 And the article was included in Journal of Photochemistry and Photobiology, A: Chemistry in 2021. The article conveys some information:
We report herein a new biphenylcarbonitrile derivative, 4′-hydroxy-3′ -((2-imidazolylimino) methyl)-4-biphenyl carbonitrile (HIBC), which interestingly exhibits an aggregation-induced emission property. HIBC was employed for selective dual mode (fluorimetric and colorimetric) assay of HSO3- ions in nearly 100% aqueous medium at pH 7.4. The nucleophilic addition of HSO3- on the imino group in HIBC breaks its π-electron conjugation and results in a noticeable absorption and fluorescence spectral changes accompanied by a visible color change. Moreover, the formation of anionic addition product weakened the aggregation effect and meanwhile inhibited ESIPT process in HIBC, causing quenching of keto fluorescence of the probe. The probe shows good selectivity for HSO3- ions over all other competitive anions, which renders it a promising candidate for ratiometric fluorescent assay of HSO3- in aqueous systems. The limit of detection is 1.83 x 10-7 mol/L. For the practical applicability, handy paper strips were fabricated from HIBC for convenient recognition of HSO3-. Addnl., HIBC was applied for the living HeLa cells bio-imaging. In the experiment, the researchers used many compounds, for example, 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7COA of Formula: C7H7N3)
1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.COA of Formula: C7H7N3
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem