Zhang, Jianwei; Zhang, Yanshi; Schnatter, Wayne F. K.; Herndon, James W. published the artcile< Coupling of N-heterocycle-fused enyne aldehydes with γ,δ-unsaturated Fischer carbene complexes>, Application In Synthesis of 36947-69-0, the main research area is aldehyde enyne heterocyclic preparation coupling unsaturated Fischer carbene; heterocycle polycyclic preparation.
The coupling of γ,δ-unsaturated Fischer carbene complexes, e.g. H2C:CHCH2CH2C(OMe):Cr(CO)5 with enyne aldehyde derivatives fused to indole, imidazole, and pyrazole ring systems, e.g. I (R1 = Me3Si, n-Bu; R2 = PhCH2, PhCHMe, ribofuranosyl; R3 = H, Me3C, Ph), has been examined The reaction leads to heterocycles fused to the hydronaphthalene ring system, e.g. II, in a single step. The products of the reaction feature heterocycles fused either to benzene rings or to a cyclohexane ring. The product distribution correlates with the electronic richness of the heterocyclic ring. A moderate degree of diastereoselectivity was observed using heterocycles featuring chiral nitrogen substituents.
Organometallics published new progress about Alkenynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 36947-69-0 belongs to class imidazoles-derivatives, and the molecular formula is C7H12N2, Application In Synthesis of 36947-69-0.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem