Khalil-Moghaddam, Shiva; Shahvelayati, Ashraf Sadat; Aliahmadi, Atousa published the artcile< Synthesis and antioxidant properties of two new derivatives of indeno-benzofuran>, Safety of 1-carboxymethyl-3-methylimidazolium chloride, the main research area is pyrogallol ninhydrin adduct preparation green chem antioxidant.
Ninhydrin reacts with poly-phenols in different ratios to produce tetracyclic adducts. Here, pyrogallol was used as a polyphenol compound In the company of acidic ionic liquid (AIL), there was a selective reaction between the ortho-site of polyphenol and the ninhydrin’s carbonyl group. Mono-adduct (1:1) and bis-adduct (2:1) were prepared using 1-(carboxymethyl)-3-methyl-1H-imidazolium chloride (mcmimCl) as a solvent and catalyst. Moreover, the antioxidant activity of these adducts was investigated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical assay and butylated hydroxytoluene (BHT) was considered to be standard The results indicated that mono-adduct showed the strongest antioxidant activity (IC50 = 5.289μg/mL).
Journal of Chemical Health Risks published new progress about Antioxidants. 700370-07-6 belongs to class imidazoles-derivatives, and the molecular formula is C6H9ClN2O2, Safety of 1-carboxymethyl-3-methylimidazolium chloride.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem