Guo, Pengfei; Zhang, Hao; Zhou, Jianguang; Gallou, Fabrice; Parmentier, Michael; Wang, Hui published the artcile< Micelle-Enabled Suzuki-Miyaura Cross-Coupling of Heteroaryl Boronate Esters>, Synthetic Route of 1003-21-0, the main research area is micelle catalyzed Suzuki heteroaryl boronic ester aryl heteroaryl halide; heterobiaryl synthesis.
We report a micellar protocol for Suzuki-Miyaura cross-coupling of heteroaryl boronic esters with aryl or heteroaryl halides. The micellar catalysis enables this coupling reaction to run under mild conditions, which avoids the decomposition of heteroaryl boronate esters and allows for high chemoselectivity for cross-coupling reaction with 6-chloropridine-2-boronic ester. The micellar protocol expands the scope of the cross-coupling reaction with challenging heteroaryl boronic esters and complements the existing cross-coupling methods for construction of heterobiaryl building blocks.
Journal of Organic Chemistry published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Synthetic Route of 1003-21-0.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem