Month: September 2022

COA of Formula: C13H11N3《I₂/TBHP promoted isocyanide insertion cyclization reaction for the synthesis of quinazolin fused benzoimidazole as a selective methanol detection probe》 was published in 2021. The authors were Ahmadi, Fereshteh;Ahmadi, Nafiseh;Balmohammadi, Yaser;Naimi-Jamal, Mohammad Reza;Bazgir, Ayoob, and the article was included in《Catalysis Communications》. The author mentioned the following in the article:

An efficient I₂/TBHP promoted isocyanide insertion cyclization reaction for the synthesis of quinazoline-fused benzoimidazoles was reported. The synthesized compounds have a unique potential to use as a selective solvatochromic fluorescence probe for methanol detection from other solvents, especially EtOH. Introducing a simple one-step method and using a more acceptable iodine mol. instead of expensive transition metal catalysts are the most important advantages of this strategy. To complete the study, the researchers used 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 COA of Formula: C13H11N3) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Application In Synthesis of 1-Ethyl-3-methyl-1H-imidazol-3-ium chlorideIn 2022, Scovazzo, Paul;Sullivan-Gonzalez, Frances;Amos, Ryan published 《Hydrogen-bond acceptance’s role in designing room temperature ionic liquid (RTIL) membranes for gas separations, Part II, beta-parameter and relative humidity impacts on membrane stability》. 《Journal of Membrane Science》published the findings. The article contains the following contents:

RTIL H-bond acceptance ability and the porous support’s polymer are important factors for RTIL-membrane stability. Under dry conditions, the stability of RTILs supported in porous polyethersulfone decreased with increasing beta-parameters. Under humid conditions, the CH₄-permeance vs. rH relationship for 1-ethyl-3-methylimidazolium trifluoromethanesulfonate changed when the porous support’s polymer changed. With proper selection of the porous support’s chem., it is possible to create RTIL-membranes that are stable over a range of rHs for both low and high Beta-parameter RTILs. However, in some RTIL/polymer supported membranes, a reversible and repeatable dual mode CH₄-permeance behavior occurs with significantly lower CH₄-permeances at elevated rHs. This dual mode is the result of RTIL/polymer interaction and not the result of changes in RTIL/transporting gas phys. chem. RTIL capillary rise vs. rH measurements are consistent with, but insufficient to state that, the dual mode results from changes in the RTIL/polymer interfacial capillary forces. Increasing gas rH leads to increased gas permeability with greater permeability enhancement for CH₄ transport. This leads to decreased CO₂/CH₄ selectivity with increasing rH. Mixed-gas CO₂/CH₄ separation data for three benchmark RTIL-membranes, verified to be stable from 0%-rH to >90%-rH, confirmed this permeance increase and selectivity decrease statement. And 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) was used in the research process.

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a solvent as well as catalyst for the depolymerization of oak wood lignin; a solvent in the hydrolysis of hemicellulose (xylan) to xylose using Brønsted acid catalysts.Application In Synthesis of 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Voskoboinik, Olexii Yu.;Stavytskyi, Viktor V.;Antypenko, Oleksii M.;Kazunin, Maksym S.;Kravtsov, Dmytro V.;Shishkina, Svetlana V.;Kovalenkoa, Sergiy I. published 《Synthesis and structure of pyrido[1,2-a]quinazoline condensed derivatives》. The research results were published in《Synthetic Communications》 in 2020.Quality Control of 2-(1H-Benzo[d]imidazol-2-yl)aniline The article conveys some information:

Present manuscript describes the synthesis and mol. structure features of novel condensed pyrido[1,2-a]quinazolines e.g., I. The above mentioned compounds e.g., I were synthesized via condensation of 2-[azolyl-(azinyl-)]anilines 2-R-4-R¹-C₆H₃NH₂ (R = 1H-1,3-benzodiazol-2-yl, 3-methyl-1H-1,2,4-triazol-5-yl, 1H-1,2,3,4-tetrazol-5-yl, 5-oxo-6-phenyl-2,5-dihydro-1,2,4-triazin-3-yl, etc.; R¹ = H, Br) with 5-oxohexanoic acid. The tandem condensation intermediates e.g., II were isolated and cyclized under various conditions. The structures of synthesized compounds e.g., I were confirmed by LC-MS and NMR-spectroscopy. The existence of the e.g., I mols. as superposition of two resonance structures was detected by the X-Ray anal. To complete the study, the researchers used 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Quality Control of 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Tu, Jiguo;Chang, Cheng;Wang, Mingyong;Guan, Wei;Jiao, Shuqiang published 《Stable and low-voltage-hysteresis zinc negative electrode promoting aluminum dual-ion batteries》 in 2022. The article was appeared in 《Chemical Engineering Journal (Amsterdam, Netherlands)》. They have made some progress in their research.SDS of cas: 65039-09-0 The article mentions the following:

Compared with the widely developed pos. electrodes, the research on the high stability neg. electrodes is far from in-depth in nonaqueous Al batteries. In order to fundamentally solve these key problems, including Al dendrites, corrosion and pulverization, it is urgent to develop an alternative stable neg. electrode. Herein, the corrosion-resistant, low-voltage-hysteresis and stable Zn is demonstrated as a promising neg. electrode. Since the deposited Al particles on the Zn electrode are prior to Zn in the stripping reaction, Zn electrode can remain good structural integrality, thus presenting great cycling stability and corrosion resistance. Importantly, the results in Al-Zn sym. cells indicate that Zn possesses the ultra-low voltage hysteresis (∼17 mV at 0.5 mA cm^-2), superior cycling stability (800 cycles at 1.0 mA cm^-2) and Al plating/stripping reversibility characteristics. Addnl., the Zn-graphite full battery based on Zn as neg. electrode and flake graphite as pos. electrode delivers stable discharge capacity of 81.1 mAh g^-1 over 300 cycles. The results in this work open an effective approach for constructing corrosion-resistant, low-voltage-hysteresis and stable neg. electrode, further indicating that Zn is great promising as neg. electrode for Al dual-ion batteries. And 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) was used in the research process.

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a solvent as well as catalyst for the depolymerization of oak wood lignin; a solvent in the hydrolysis of hemicellulose (xylan) to xylose using Brønsted acid catalysts.SDS of cas: 65039-09-0

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Electric Literature of C13H11N3In 2021, Meng, Xiang-He;Wu, Dan-Ni;Zhang, Yu-Jia;Zhao, Yu-Long published 《PPTS-Catalyzed Bicyclization Reaction of 2-Isocyanobenzaldehydes with Various Amines: Synthesis of Diverse Fused Quinazolines》. 《Advanced Synthesis & Catalysis》published the findings. The article contains the following contents:

A PPTS (pyridinium p-toluenesulfonate)-catalyzed bicyclization reaction of 2-isocyanobenzaldehydes 2-NC-4-R-5-R¹C₆H₂CHO (R = H, Br, OMe; R¹ = H, Cl, F, OMe) as 1,5-dielectrophiles with various amines R²NH₂ (R² = 3-hydroxypropyl, 2-amino-4,5-difluorophenyl, 2-(1H-pyrrol-1-yl)benzen-1-yl, etc.) has been developed. The reaction not only provides a simple and efficient strategy for the assembly of structurally diverse fused quinazoline derivatives e.g., I from readily available substrates under metal-free and mild conditions in a single step with only water and hydrogen as the byproducts, but also opens the way to the application of o-formyl arylisocyanides in the synthesis of nitrogen-containing heterocycles e.g., I. And 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) was used in the research process.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Electric Literature of C13H11N3) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Nawrot, I.;Czerwinska, Katarzyna;Machura, B.;Kruszynski, R. published 《Synthesis, structural diversity and luminescent properties of cadmium(II) coordination assemblies with 2-(2-aminophenyl)-1H-benzimidazole and pseudohalide ions》 in 2017. The article was appeared in 《Journal of Luminescence》. They have made some progress in their research.Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline The article mentions the following:

A systematic investigation of Cd(II)-(apbim)-X systems (apbim=2-(2-aminophenyl)-1H-benzimidazole and X=N^–₃,SCN^– and N(NC)^–₂) was conducted, and the following cadmium(II) coordination compounds [Cd(N₃)₂(apbim)]_n•nMeOH (1), [Cd(SCN)₂(apbim)]_n•nMeOH (2), [Cd(dca)(apbim)₂]_n•n(NO₃) (3), [Cd(SCN)₂(apbim)₂] (4) and [Cd(dca)₂(apbim)₂]•H₂O (5) were successfully synthesized and characterized by single-crystal diffraction, X-ray powder diffraction (XRPD), differential scanning calorimetry (DSC) anal. and IR spectroscopy. The luminescent properties of 2-(2-aminophenyl)-1H-benzimidazole and cadmium(II) coordination compounds were studied in solution (4 and 5) and solid state (1-5). The studies revealed that the solid state architecture and solid state photoluminescent properties of the Cd(II)-apbim-X systems (X=N₃, NCS^– and dca^–) are strongly influenced by intermol. interactions. To complete the study, the researchers used 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthetic Route of C6H11ClN2《Soluble Electrolyte-Coordinated Sulfide Species Revealed in Al-S Batteries by Nuclear Magnetic Resonance Spectroscopy》 was published in 2022. The authors were Jay, Rahul;Jadhav, Ankur L.;Gordon, Leo W.;Messinger, Robert J., and the article was included in《Chemistry of Materials》. The author mentioned the following in the article:

Rechargeable aluminum-sulfur (Al-S) batteries have recently garnered significant interest to the low cost, earth abundance, safety, and high theor. capacity of the electrode materials. However, Al-S batteries exhibit many challenges that plague other metal-sulfur battery systems, including significant capacity fade of the sulfur electrode due to the formation of electrolyte-soluble reaction intermediates. Here, Al-S cells using chloroaluminate-containing ionic liquid electrolytes were investigated up from the mol. level using multidimensional solid-state ²⁷Al MAS NMR spectroscopy, XPS, X-ray diffraction (XRD), and electrochem. measurements. Solid-state ²⁷Al single-pulse NMR measurements acquired on cycled sulfur electrodes containing electrolyte-soaked separator revealed multiple discharge products, which were distinguished into liquid- and solid-phase products based on ²⁷Al chem. exchange and nutation NMR experiments During discharge, electrolyte-soluble sulfide species form that coordinate with the AlCl₄^– chloroaluminate anions, resulting in (S_xAlCl₄)^y- electrolyte complexes. These electrolyte-coordinated sulfide species persist upon charge, resulting in the loss of active mass that explains the significant capacity fade observed upon galvanostatic cycling. XPS, XRD, and solid-state ²⁷Al NMR measurements reveal that solid amorphous Al₂S₃ forms reversibly upon discharge. The results highlight the technol. importance of understanding how electrolyte-soluble sulfide species coordinate with the complex electroactive species used in multivalent metal-sulfur batteries, which can affect their reversibility and electrochem. properties. To complete the study, the researchers used 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) .

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a solvent as well as catalyst for the depolymerization of oak wood lignin; a solvent in the hydrolysis of hemicellulose (xylan) to xylose using Brønsted acid catalysts.Synthetic Route of C6H11ClN2

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Muslim, Mohd;Faizi, Serajul Haque Md.;Ali, Arif;Afzal, Mohd;Ahmad, Musheer;Dege, Necmi;Mashrai, Ashraf published 《Crystal structure and Hirshfeld surface analysis of [2-(1H-benzimidazol-2-yl-κN³)aniline-κN]dichloridozinc(II) N,N-dimethylformamide monosolvate》 in 2021. The article was appeared in 《Acta Crystallographica, Section E: Crystallographic Communications》. They have made some progress in their research.Reference of 2-(1H-Benzo[d]imidazol-2-yl)aniline The article mentions the following:

The title compound, [ZnCl₂(C₁₃H₁₁N3)]·C₃H₇NO, crystallized in the monoclinic crystal system in space group P2₁/n. The asym. unit contains one neutral complex mol., which consists of a zinc ion, a bidentate ligand, and two chlorido ligands with DMF monosolvate. The ligand has two moieties, a benzimidazole and an aniline group. The benzimidazole and aniline planes are not coplanar, subtending a dihedral angle of 18.24 (8)°. The Zn(II) ion shows distorted tetrahedral geometry, being coordinated by an imidazole N atom, the aniline N atom, and two chlorido ligands. The packing features N-H···O, N-H···Cl, C-H···Cl hydrogen bonding. And 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) was used in the research process.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Reference of 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Yin, Zhi-Yuan;Hu, Jing-Han;Gui, Kai;Fu, Qing-Qing;Yao, Ying;Zhou, Fu-Long;Ma, Li-Long;Zhang, Zhi-Peng published 《AIE based colorimetric and “turn-on” fluorescence Schiff base sensor for detecting Fe³⁺ in an aqueous media and its application》 in 2020. The article was appeared in 《Journal of Photochemistry and Photobiology, A: Chemistry》. They have made some progress in their research.Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline The article mentions the following:

A novel AIE active dual-channel coumarin derivatives, chemosensor G1, was synthesized and used for detecting Fe³⁺ (in water solution) in DMSO/H₂O (1:9, volume/volume, pH = 7.2) binary solutions, which induced the color of solution of G1 from yellow to shallow orange and increased the fluorescence emission, indicating that G1 could act as a corking colorimetric and “turn-on” fluorescence probe for detecting Fe³⁺. What′s more, sensor G1 has good anti-interference toward Ca²⁺, Hg²⁺, Cu²⁺, Ag⁺, Cd²⁺, Co²⁺, Ni²⁺, Mg²⁺, Pb²⁺, Zn²⁺ and Cr³⁺. Notably, the actual usage of sensor G1 was further demonstrated by logic gates and test kits. And 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) was used in the research process.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Martinez-Ariza, Guillermo;McConnell, Nicholas;Hulme, Christopher published 《One-Pot Two-Step Multicomponent Process of Indole and Other Nitrogenous Heterocycles or Amines toward α-Oxo-acetamidines》. The research results were published in《Organic Letters》 in 2016.SDS of cas: 5805-39-0 The article conveys some information:

A cesium carbonate promoted three-component reaction of N-H containing heterocycles, primary or secondary amines, arylglyoxaldehydes, and anilines is reported. The key step involves a tandem sequence of N-1 addition of a heterocycle or an amine to preformed α-iminoketones, followed by an air- or oxygen-mediated oxidation to form α-oxo acetamidines. The scope of the reaction is broad, and this novel methodol. is applied toward the synthesis of various polycyclic heterocycles. To complete the study, the researchers used 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 SDS of cas: 5805-39-0) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem