Month: September 2022

Product Details of 5805-39-0《Microwave Assisted Green Synthesis of Benzimidazole Derivatives and Evaluation of Their Anticonvulsant Activity》 was published in 2019. The authors were Sahoo, Biswa Mohan;Banik, Bimal Krishna;Mazaharunnisa;Rao, Naidu Srinivasa;Raju, Bodapati, and the article was included in《Current Microwave Chemistry》. The author mentioned the following in the article:

N-(Benzimidazolylphenyl)cinnamides I (R = Ph, 2-ClC₆H₄, 4-ClC₆H₄, 4-FC₆H₄, 4-HC₆H₄) are synthesized by reaction between ortho-phenylene diamine and anthranilic acid followed by acetylation in the presence of acetic anhydride and Claisen-Schmidt condensation with substituted benzaldehydes RCHO. Both conventional and microwave irradiation technol. are followed to get the titled compounds I. The titled compounds are screened for their anticonvulsant activity and neurotoxicity. By the help of microwave synthesis, the yield of product was increased in less reaction time. So, it follows Green chem. approach by making above reactions eco-friendly. Some of the compounds exhibited significant anticonvulsant activity as compared to standard drug. And 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) was used in the research process.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Product Details of 5805-39-0) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Related Products of 65039-09-0《Revealing the multiple cathodic and anodic involved charge storage mechanism in an FeSe₂ cathode for aluminium-ion batteries by in situ magnetometry》 was published in 2022. The authors were Wang, Huaizhi;Zhao, Linyi;Zhang, Hao;Liu, Yongshuai;Yang, Li;Li, Fei;Liu, Wenhao;Dong, Xiaotong;Li, Xiangkun;Li, Zhaohui;Qi, Xiaodong;Wu, Langyuan;Xu, Yunfei;Wang, Yaqun;Wang, Kuikui;Yang, Huicong;Li, Qiang;Yan, Shishen;Zhang, Xiaogang;Li, Feng;Li, Hongsen, and the article was included in《Energy & Environmental Science》. The author mentioned the following in the article:

Rechargeable aluminum-ion batteries (AIBs) are considered to be promising alternatives to current lithium-ion batteries (LIBs), since they can have the advantages of low cost with high energy-to-price ratios. Unlike in LIBs, the charge storage mechanism in AIBs involving different ionic species is far more complicated and remains largely unexplored, which impedes further screening and optimization of cathode materials that can reversibly accommodate aluminum-based (complex) charge carriers with boosted cell performance. Here, we report a comprehensive study of the battery chem. in metal selenide based cathodes in AIBs from an integrated chem. and phys. point of view. Various in situ and ex situ characterization techniques and theor. calculations reveal that both Cl^– and AlCl₄^– can act as charge carriers in FeSe₂ cathodes during the charge process, and the Al³⁺ can also be embedded into the host upon the discharge process. Furthermore, using in situ magnetometry, the spin-polarized surface capacitance is observed in AIBs for the first time, which proves that Al³⁺ can serve as a charge compensator in the formation of space charge zones with electrons. These innovative findings provide unprecedented insight into the charge storage mechanism of AIBs. To complete the study, the researchers used 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) .

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a starting material for the preparation of 1-ethyl-3-methylimidazolium chloride/tetrafluoroborate (EMI.Cl.BF4) molten salt for electrochemical studies; a solvent as well as catalyst for the depolymerization of oak wood lignin.Related Products of 65039-09-0

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Ha, Son;Hyun, Jong Chan;Kwak, Jin Hwan;Lim, Hee-Dae;Youn, Beom Sik;Cho, Sungmin;Jin, Hyoung-Joon;Lim, Hyung-Kyu;Lee, Sang Moon;Yun, Young Soo published 《Waste-induced pyrolytic carbon nanotube forest as a catalytic host electrode for high-performance aluminum metal anodes》. The research results were published in《Chemical Engineering Journal (Amsterdam, Netherlands)》 in 2022.Related Products of 65039-09-0 The article conveys some information:

A multivalent aluminum metal anode (AMA) can deliver high specific/volumetric capacities of 2,980 mA h g^-1/8,040 mA h cm^-3 in an ionic liquid-AlCl₃ electrolyte system. However, the large concentration overpotential of AMA induced by its distinctive anion-mediated aluminum metal redox mechanism causes poor rate capabilities and insufficient round-trip efficiencies, limiting its application in rechargeable aluminum batteries (RABs). In this paper, we report a novel strategy of using a carbonaceous catalytic host electrode for high-performance AMA. The targeted carbon electrode should have a high active surface area, strong interaction with ionic charge carriers, well-developed electronic pathways, and macroporous internal structures to accommodate incessantly deposited metals. In this regard, a 3D-structured carbon nanotube forest (CNT-F) was fabricated from waste polyolefins by a simple pyrolysis process as an optimal candidate for the catalytic host electrode. The waste-induced pyrolytic CNT-Fs (WP-CNT-F) had large open surface areas covered with multitudinous intrinsic carbon defects, on which uniform aluminum reduction reactions occurred concurrently, leading to significantly lower concentration overpotentials. In addition, the WP-CNT-Fs exhibited high coulombic efficiencies of 99.4-99.8% over a wide range of current densities (0.5-4.0 mA cm^-2) and great cycling stabilities over 1,000 cycles. The superior electrochem. performances of the WP-CNT-F-based AMA were demonstrated in the RAB full cells with a com. graphite cathode, affording a high specific energy and a high power d. of ∼132.2 W h kg^-1electrode and 10,230 W kg^-1electrode, resp., along with outstanding cycling stabilities over 2,500 cycles.1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) were involved in the experimental procedure.

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a starting material for the preparation of 1-ethyl-3-methylimidazolium chloride/tetrafluoroborate (EMI.Cl.BF4) molten salt for electrochemical studies; a solvent as well as catalyst for the depolymerization of oak wood lignin.Related Products of 65039-09-0

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Name: 2-(1H-Benzo[d]imidazol-2-yl)anilineIn 2021, Li, Jia-Bin;Zheng, Han-Wen;Wu, Min;Liang, Qiong-Fang;Yang, Dong-Dong;Zheng, Xiang-Jun;Tan, Hong-Wei published 《Multistimulus Response of Two Tautomeric Zn(II) Complexes and Their White-Light Emission Based on Different Mechanisms》. 《Inorganic Chemistry》published the findings. The article contains the following contents:

A triphenylamine (TPA)-based 2H-quinazoline Zn(II) complex (Q-TPA-Zn) exhibiting dual fluorescence and phosphorescence emission in the solid state was designed and prepared It possesses mechanochromic luminescence and thermochromic luminescence properties. In the solid state, the white afterglow luminescence could be observed at 77 K (CIE_xy: 0.27, 0.33) while cyan luminescence could be observed at 297 K. After thermolysis at 300 °C, Q-TPA-Zn could be transformed into Schiff base complex S-TPA-Zn with white fluorescence in the powder state (CIE_xy: 0.32, 0.38), in methanol (CIE_xy: 0.32, 0.39), and in DMF (CIE_xy: 0.26, 0.32) at room temperature This arises from dual emission of normal* emission and tautomeric* emission induced by excited-state intramol. proton transfer (ESIPT) from the benzimidazole NH group to the Schiff base N atom. Q-TPA-Zn could also be transformed into its isomeric form, S-TPA-Zn, through photochem. ring-opening reaction upon irradiation under 365 nm in the solution, exhibiting high-contrast photochromic luminescence. Interestingly, S-TPA-Zn could further be transformed into its zwitterionic isomer after continuous irradiation The same ring-opening reaction could also take place for the organic compound Q-TPA via heating or 365 nm irradiation The ring-opening reaction mechanism and ESIPT emission were interpreted via theor. calculation To complete the study, the researchers used 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Khan, Salman A.;Ullah, Qasim;Parveen, Humaira;Mukhtar, Sayeed;Alzahrani, Khalid Ahmed;Asad, Mohammad published 《Synthesis and photophysical investigation of novel imidazole derivative an efficient multimodal chemosensor for Cu(II) and fluoride ions》. The research results were published in《Journal of Photochemistry and Photobiology, A: Chemistry》 in 2021.SDS of cas: 5805-39-0 The article conveys some information:

Aminophenylbenzimidazole derivative of theonyl trifluoro acetone has been designed, synthesized and characterized to sense Cu(II) and fluoride ions. The probe showed very selective colorimetric and ratiometric fluorescence changes with copper(II), turn-on fluorescence behavior with fluoride ions. ESI-MS anal. and jobs plots anal. provided the information about the interaction mode between Cu(II) and the probe. D. functional theory calculations carried out on the probe with/without Cu(II) and fluoride ions to support the observed photophys. changes. The Probe can be utilized to detect Cu(II) ions via electrochem. detection and hence it can be used to detect copper ions by multiple modes. The fluorescence and absorbance change with fluoride ions showing that the probe is very sensitive towards fluoride ions among other anions. The detection limits for the detection of Cu(II) and fluoride ions were found to be 23 nM and 0.54 nM resp. To complete the study, the researchers used 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 SDS of cas: 5805-39-0) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

SDS of cas: 65039-09-0《Ultralow-Power and Multisensory Artificial Synapse Based on Electrolyte-Gated Vertical Organic Transistors》 was published in 2022. The authors were Liu, Guocai;Li, Qingyuan;Shi, Wei;Liu, Yanwei;Liu, Kai;Yang, Xueli;Shao, Mingchao;Guo, Ankang;Huang, Xin;Zhang, Fan;Zhao, Zhiyuan;Guo, Yunlong;Liu, Yunqi, and the article was included in《Advanced Functional Materials》. The author mentioned the following in the article:

Bioinspired electronics have shown great potential in the field of artificial intelligence and brain-like science. Low energy consumption and multifunction are key factors for its application. Here, multisensory artificial synapse and neural networks based on electrolyte-gated vertical organic field-effect transistors (VOFETs) are first developed. The channel length of the organic transistor is scaled down to 30 nm through crosslinking strategy. Owing to the short channel length and extremely large capacitance of the elec. double layer formed at the electrolyte-channel interface, the min. power consumption of one synaptic event is 0.06 fJ, which is significantly lower than that required by biol. synapses (1-10 fJ). Moreover, the artificial synapse can be trained to learn and memory images in a 5 x 5 synapse array and emulate the human brain′s spatiotemporal information processing and sound azimuth detection. Finally, the artificial tongue is designed using the synaptic transistor that can discriminate acidity. Overall, this study provides new insights into realizing energy-efficient artificial synapses and mimicking biol. sensory systems. To complete the study, the researchers used 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) .

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a starting material for the preparation of 1-ethyl-3-methylimidazolium chloride/tetrafluoroborate (EMI.Cl.BF4) molten salt for electrochemical studies; a solvent as well as catalyst for the depolymerization of oak wood lignin.SDS of cas: 65039-09-0

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

COA of Formula: C13H11N3《Synthesis, characterization, X-ray crystal structures of heterocyclic Schiff base compounds and in vitro cholinesterase inhibition and anticancer activity》 was published in 2017. The authors were Arafath, Azharul Md.;Adam, Farook;Al-Suede, Fouad Saleih R.;Razali, Mohd. R.;Ahamed, Mohamed B. Khadeer;Abdul Majid, Amin Malik Shah;Hassan, Mohd. Zaheen;Osman, Hasnah;Abubakar, Saifullah, and the article was included in《Journal of Molecular Structure》. The author mentioned the following in the article:

Four heterocyclic embedded Schiff base derivatives, (benzimidazo[1,2-c]quinazolin-6-yl)methoxyphenol I and II [R = 3-OH-4-OMe, 2-OH-5-OMe; R¹ = 5-methyl-2-pyridyl, 2-(1,3-benzothiazol-2-yl)phenyl] were synthesized and characterized by m.p., elemental anal., FTIR, ¹H, ¹³C NMR and UV-visible spectral data. The structures of compounds I and II [R = 2-OH-5-OMe, R¹ = 5-methyl-2-pyridyl; 3-OH-4-OMe, 2-(1,3-benzothiazol-2-yl)phenyl] were successfully established through single crystal X-ray diffraction anal. In-vitro cholinesterase inhibition assays showed that the cyclized derivative I displayed higher BuChE enzyme inhibitory activity with IC₅₀ value of 1.45 ± 0.09 μM. The anti-proliferative efficacies of the compounds were also evaluated using human colorectal HCT 116 and breast MCF-7 adenocarcinoma cell lines. In addition, a human normal endothelial cell line (Ea.hy926) was also tested to assess the safety and selectivity of the compounds towards normal and cancer cells, resp. Among the compounds tested, compound II [R = 3-OH-4-OMe, 2-(1,3-benzothiazol-2-yl)phenyl] displayed potent cytotoxic effect (IC₅₀ = 34 μM) against HCT 116 cells with highest selectivity index of 3.1 with respect to the normal endothelial cells. Whereas, compound II [R = 2-OH-5-OMe, R¹ = 5-methyl-2-pyridyl] exhibited significant anti-proliferative effect (IC₅₀ = 21.1 μM) against MCF-7 cells with highest selectivity index of 3.3 with respect to the normal endothelial cells. The docking result of these compounds against hAChE showed potent activities with different binding modes. These compounds could be a promising pharmacol. agent to treat cancer and Alzheimer’s disease. The experimental procedure involved many compounds, such as 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 COA of Formula: C13H11N3) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Xiong, Yucong;Wang, Kaizhi;Ma, Lei;Zhu, Jiukang;Miao, Yujia;Gong, Li;Mu, Xiao;Wan, Jiang;Li, Rong published 《Bimetallic CoMoO₄@C nanorod catalyzes one-pot synthesis of benzimidazoles from benzyl alcohol and o-phenylendiamine without alkali》 in 2022. The article was appeared in 《Applied Organometallic Chemistry》. They have made some progress in their research.Recommanded Product: 2-(1H-Benzo[d]imidazol-2-yl)aniline The article mentions the following:

Benzimidazoles possess a series of applications for industrial chem. and biomedicine. However, the complicated synthetic steps and harsh reaction conditions limit its further development. Herein, authors reported an efficient, environmentally friendly, and stable bimetallic CoMoO4@C catalyst, which used low-cost cobalt and molybdenum as the basic raw material. In base-free conditions, it has been proved that the yield could achieve to 99.9% for the synthesis of benzimidazoles with liberating water as the sole byproduct, and the catalyst remains stable and efficient even after five successive cycle tests. Addnl., experiments and characterizations confirm the good oxidation activity of the catalyst benefits from the numerous oxygen vacancies provided by the high concentration of low-valent cobalt (Co²⁺) and the doping of carbon improves the intermol. transport of electrons. Furthermore, this strategy could potentially be applied in the industrial production of benzimidazoles. And 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) was used in the research process.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Recommanded Product: 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Name: 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride《The mechanisms involved into the inhibitory effects of ionic liquids chemistry on adsorption performance of ciprofloxacin onto inorganic minerals》 was published in 2022. The authors were Chen, Jiuyan;Xu, Yalei;Zheng, Zhongqin;Wei, Qiqi;Farooq, Usman;Lu, Taotao;Chen, Weifeng;Qi, Zhichong, and the article was included in《Colloids and Surfaces, A: Physicochemical and Engineering Aspects》. The author mentioned the following in the article:

The ionic liquids (ILs) can influence the adsorption of antibiotics on minerals but there was ambiguity about mechanisms. Herein, we demonstrated the adsorption characteristics of ciprofloxacin (CIP) onto ferrihydrite and montmorillonite by various soluble ILs. Five imidazolium-based ILs with different alkyl chain lengths ([C₂mim]Cl, [C₄mim]Cl, [C₆mim]Cl) and counteranions ([C₄mim][TOS] and [C₄mim][PF₆]) were employed. The results validated that ILs could suppress CIP adsorption on both minerals due to the adsorption site competition between cations and CIP mols., steric hindrance induced by long alkyl chains of ILs, and electrostatic interaction. Interestingly, the adsorption-inhibition effects of ILs were almost unchanged with the lengthening alkyl chain for ferrihydrite, which were ascribed to the comparable adsorption capacities of the three ILs on ferrihydrite. Whereas, the effects of ILs on CIP adsorption onto montmorillonite followed the order of [C₆mim]Cl > [C₄mim]Cl > [C₂mim]Cl owing to the adsorption site competition and steric hindrance effects on the ILs increased with the lengthening alkyl chain. Furthermore, the inhibitory effects of ILs on CIP adsorption onto both studied minerals were also dependent on the counteranions (kept the same cation ([C₄mim]+)) and in the following order of [C₄mim][PF₆] > [C₄mim][TOS] > [C₄mim]Cl, which was mainly ascribed to the differences of anions in the ion sizes and the binding affinities to minerals. Addnl., the extent of the inhibitory impact of [C₄mim][TOS] on CIP adsorption onto ferrihydrite declined with increasing solution pH from 5.0 to 9.0, which was attributed to the amounts of adsorbed [TOS]^– declined with increasing pH. Contrarily, for montmorillonite, the extent increased with increasing pH, owing to increase in adsorption site competition and steric effect at higher pH conditions. Our findings emphasize the significance of emerging contaminants in understanding the antibiotic environmental behavior in eco-environmental systems. The experimental procedure involved many compounds, such as 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) .

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a starting material for the preparation of 1-ethyl-3-methylimidazolium chloride/tetrafluoroborate (EMI.Cl.BF4) molten salt for electrochemical studies; a solvent as well as catalyst for the depolymerization of oak wood lignin.Name: 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Sulaimon, Aliyu Adebayo;Masri, Asiah Nusaibah;Jamil Sabri, Umar Abdul Aziz;Adeyemi, Bamikole Joshua published 《Predicting naphthenate precipitation and evaluating the effect of ionic liquids on its deposition》 in 2022. The article was appeared in 《Journal of Petroleum Science & Engineering》. They have made some progress in their research.Safety of 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride The article mentions the following:

Naphthenic acids that are naturally carboxylic compounds contained in heavy crude oil are the main source of corrosion and blockage in a crude oil pipeline. The blockage is due to the formation of naphthenate deposits through a reaction of naphthenic acid with metal ions present in the crude oil. In the present study, model oil is used to evaluate the effect of water cut in the range of 10%-90%, brine pH in the range of 6-10, Ca²⁺ concentration in the range of 0.5%-2.5% and temperature in the range of 30 °C-60 °C towards naphthenate deposition with the aid of response surface methodol. NMR (NMR) and Fourier Transform IR (FTIR) were used to evaluate the structure of the naphthenic acids used. Results show that Ca²⁺ concentration contributes mostly to the naphthenate deposition, followed by brine pH, water cut and temperature Two math. models were developed to predict the final pH of the oil-brine system and the mass of precipitates with average relative errors (AREs) of 0.0328 and 0.0325 resp. The effects of two ionic liquids (ILs), 1-ethyl-3-methylimidazolium chloride (EMIM-Cl) and 1-butyl-3-methylimidazolium chloride (BMIM-Cl), on naphthenates precipitation, were also evaluated. Anal. showed that both ILs can reduce the amount of naphthenate deposited, with the BMIM-Cl showing better performance than the EMIM-Cl. And 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) was used in the research process.

1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a solvent as well as catalyst for the depolymerization of oak wood lignin; a solvent in the hydrolysis of hemicellulose (xylan) to xylose using Brønsted acid catalysts.Safety of 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem