Voskoboinik, Olexii Yu.;Stavytskyi, Viktor V.;Antypenko, Oleksii M.;Kazunin, Maksym S.;Kravtsov, Dmytro V.;Shishkina, Svetlana V.;Kovalenkoa, Sergiy I. published 《Synthesis and structure of pyrido[1,2-a]quinazoline condensed derivatives》. The research results were published in《Synthetic Communications》 in 2020.Quality Control of 2-(1H-Benzo[d]imidazol-2-yl)aniline The article conveys some information:
Present manuscript describes the synthesis and mol. structure features of novel condensed pyrido[1,2-a]quinazolines e.g., I. The above mentioned compounds e.g., I were synthesized via condensation of 2-[azolyl-(azinyl-)]anilines 2-R-4-R1-C6H3NH2 (R = 1H-1,3-benzodiazol-2-yl, 3-methyl-1H-1,2,4-triazol-5-yl, 1H-1,2,3,4-tetrazol-5-yl, 5-oxo-6-phenyl-2,5-dihydro-1,2,4-triazin-3-yl, etc.; R1 = H, Br) with 5-oxohexanoic acid. The tandem condensation intermediates e.g., II were isolated and cyclized under various conditions. The structures of synthesized compounds e.g., I were confirmed by LC-MS and NMR-spectroscopy. The existence of the e.g., I mols. as superposition of two resonance structures was detected by the X-Ray anal. To complete the study, the researchers used 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .
2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Quality Control of 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem