Shree, Ganesan Jeya;Sivaraman, Gandhi;Siva, Ayyanar;Chellappa, Duraisamy published 《Anthracene- and pyrene-bearing imidazoles as turn-on fluorescent chemosensor for aluminum ion in living cells》 in 2019. The article was appeared in 《Dyes and Pigments》. They have made some progress in their research.Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline The article mentions the following:
A newly designed 2-(2-Aminophenyl)-1H-benzimidazole integrated anthracene/pyrene derivatives as efficient chemosensors were synthesized. The probes N-(anthracen-9-ylmethylene)-2-(1H-benzo[d]imidazol-2-yl)aniline (ANP) and N-(pyren-1-ylmethylene)-2-(1H-benzo[d]imidazol-2-yl)-aniline (PYP) exhibited high selectivity and sensitivity towards Al3+ ion over other interfering and competing cations in aqueous solution Job’s plot anal. reveals that the interaction of ANP/PYP with Al3+ was 1:1 binding stoichiometry. The detection limit of probes ANP and PYP for Al3+ ions are 1.85 × 10-7 M and 1.08 × 10-7 M, resp. The DFT/TD-DFT calculations have also been revealed that the ICT mechanism is responsible for the observed photophys. changes. Moreover, the probes ANP and PYP were applicable to image intracellular Al3+ ions in living cells via confocal fluorescence microscopy technique. The experimental procedure involved many compounds, such as 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .
2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem