Lohar, Somenath;Maji, Abhishek;Pal, Siddhartha;Mukhopadhyay, Subhra Kanti;Nag, Dipta;Demitri, Nicola;Chattopadhyay, Pabitra published 《Naphthalimide-Based Turn-On Fluorosensor for Aqueous Sulfide Ions for Staining in Living Cells》. The research results were published in《ChemistrySelect》 in 2017.Application In Synthesis of 2-(1H-Benzo[d]imidazol-2-yl)aniline The article conveys some information:
A newly synthesized and characterized naphthalimide derivative (L1) acts as a highly sensitive chemosensor for aqueous sulfide ions in water/DMSO (3:1, volume/volume) medium as L1 offers distinctive reactive properties toward aqueous sulfide ions to be converted to L1A of potential turn-on fluorescent properties over other competitive anions. Gradual addition of aqueous sulfide ions led to the formation of in situ L1A compound which showed a single point fluorescence enhancement based on intramol. charge transfer (ICT). To establish this new interesting pathway in favor of ICT for sensing sulfide ions, the detailed spectroscopic studies of other three similar type new 1,8-naphthalimide based organic probes (L2, L3 and L4) duly structurally characterized including theor. (DFT) studies have been carried out systematically. The probe (L1) detects aqueous sulfide ions as low as 2.4μM in at biol. pH within a very short responsive time (15-20 s) and this non-cytotoxic the probe, L1 is also useful in acquiring the fluorescent image of the distribution of sulfide ions in living cells using fluorescence microscope. And 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) was used in the research process.
2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Application In Synthesis of 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem