Lian, Kai;Liu, Yang;Teng, Bo;Zhao, Yongjie published 《Phase equilibrium and ionic liquid partitioning in aqueous two-phase system composed of alcohol and small molecule compound》 in 2022. The article was appeared in 《Journal of the Iranian Chemical Society》. They have made some progress in their research.Application In Synthesis of 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride The article mentions the following:
In this study, liquid-liquid equilibrium data of an aqueous two-phase system (ATPS) composed of alcs. (ethanol, 1-propanol, or 2-propanol) and small-mol. organic compound (sodium citrate, sodium tartrate, sucrose, maltose, and lactose) was extensively investigated at 298.1 K ± 0.1 K. The binodal curves were summarized through the empirical nonlinear equations with the lowest standard deviation. The contents of alcs. and organic salts in ATPS were accurately determined by gas chromatog. and UV spectrophotometer. The phase-forming abilities of alcs. were ranked in the following order, 1-propanol > 2-propanol > ethanol, resp. The ATPS composed of saccharides was difficult to form two phases due to the high viscosity. The salting-out abilities of sodium citrate (C6H5Na3O7) were better than sodium tartrate. 1-propanol/ C6H5Na3O7ATPS had larger biphase areas, it was further applied to concentrate various ionic liquids including [C2mim]BF4, [C4mim]BF4, [C4mim]Cl and [C8mim]Cl. The results showed that alc./organic salt ATPS had a better extraction rate to imidazole-type ionic liquids Ionic liquids were mainly distributed in the top phase (alc.-rich phase). And 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride (cas: 65039-09-0) was used in the research process.
1-Ethyl-3-methyl-1H-imidazol-3-ium chloride(cas: 65039-09-0) is an imidazolium chloride ionic liquid that can be used as:a solvent as well as catalyst for the depolymerization of oak wood lignin; a solvent in the hydrolysis of hemicellulose (xylan) to xylose using Brønsted acid catalysts.Application In Synthesis of 1-Ethyl-3-methyl-1H-imidazol-3-ium chloride
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem