Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Category: imidazoles-derivatives.
Chen, Jiguang;Sun, Dandan;Xu, Shaomin;Fu, Yongming;Yang, Yukun;Ma, Jie research published 《 A Microfiber Sensor for the Trace Copper Ions Detection Based on Ternary Sensitive film》, the research content is summarized as follows. An optic-fiber sensor for detecting the concentration of trace copper ions is proposed using a ternary cross-linked sensitive film coated on the Mach-Zehnder microfiber interferometer surface. The microfiber has a huge evanescent field offering high sensitivity to the ambient refractive index. The chelation between imidazole groups in the coated thin film and copper ions changes the refractive index of the sensor surface, which is converted into macroscopic wavelength drift in the interference spectrum. The sensitivity of the sensor is up to 7.715 x 106 nm M-1 with the detection limit of 0.0576 ppm. This sensor can effectively avoid the effect of temperature cross-response and has good specificity and stability. This study has instructive meanings for designing optical pollutant sensors with high stability and improved detection accuracy in a potentially multi-characteristic environment.
10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Category: imidazoles-derivatives
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem