Application of 5805-39-0In 2018, Chen, Dong-Sheng;Liu, Shu-Jun;Lu, Wen-Qiang;Wang, Xiang-Shan published 《Green synthesis of 6-aryl-5,6-dihydrobenzo[4,5]imidazo[1,2-c]quinazoline derivatives in ionic liquid under catalyst-free conditions》. 《Journal of Heterocyclic Chemistry》published the findings. The article contains the following contents:
Using ionic liquids as green media, a series of 6-arylbenzimidazolo[1,2-c]quinazoline derivatives I [R1 = 3-Cl, 4-Br, 3,5-(MeO)2, etc.] was synthesized via reaction of 2-(1H-benzo[d]imidazol-2-yl)aniline and benzaldehydes in the air. The intermediate products of 6-arylbenzimidazolo[1,2-c]quinazolines II [R2 = 2,4-Cl2, 2-Br, 3,5-(MeO)2, etc.] were obtained in high yields at the same conditions under nitrogen protection. The experimental procedure involved many compounds, such as 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .
2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Application of 5805-39-0) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem