Jeyanthi, D.;Joel, C.;Bennie, R. Biju;Livingston, D. Jim;Balakrishnan, C. published 《Crystal structure and chemosensing property of benzimidazole-based probe towards detection of multiple analytes – A combined experimental and DFT approach》 in 2022. The article was appeared in 《Journal of Photochemistry and Photobiology, A: Chemistry》. They have made some progress in their research.Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline The article mentions the following:
A benzimidazole derived probe [(6-(1H-indol-3-yl)-5,6-dihydrobenzo[4,5]imidazo [1,2-c]quinazoline) (IDBIQ)] was synthesized and structurally characterized by single-crystal X-ray diffraction anal. and spectroscopic methods. The probe IDBIQ crystallizes in a monoclinic P21/c space group which is found to be highly sensitive and also selective towards the analytes HgII, F– and histidine. The probe exhibits turn-off fluorescence for HgII and histidine while it is ratiometric towards F– ions. These quenching and ratiometric fluorescent changes have been further explored by 1H NMR titrations and DFT/TD-DFT calculations The limit of detection of the probe towards the analytes was found to be in nano-molar range and the receptor was observed to bind with the analytes in 1:1 stoichiometric manner. And 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) was used in the research process.
2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem