The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: (6-Chloropyridin-2-yl)methanamine, is researched, Molecular C6H7ClN2, CAS is 188637-75-4, about Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group, the main research direction is morpholine aspartate HIV protease inhibitor preparation; HIV; MK-8718; inhibitor; protease.Name: (6-Chloropyridin-2-yl)methanamine.
A novel HIV protease inhibitor was designed using a morpholine core as the aspartate binding group. Anal. of the crystal structure of the initial lead bound to HIV protease enabled optimization of enzyme potency and antiviral activity. This afforded a series of potent orally bioavailable inhibitors of which MK-8718 was identified as a compound with a favorable overall profile.
This compound((6-Chloropyridin-2-yl)methanamine)Name: (6-Chloropyridin-2-yl)methanamine was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem