Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Inorganic Chemistry called Versatile Route to trans-Platinum(II) Complexes via Manipulation of a Coordinated 3-(Pyridin-3-yl)propanoic Acid Ligand, Author is Cabrera, Silvia; Navas, Francisco; Matesanz, Ana I.; Maroto, Marta; Riedel, Tina; Dyson, Paul J.; Quiroga, Adoracion G., which mentions a compound: 3724-19-4, SMILESS is OC(=O)CCC1=CC=CN=C1, Molecular C8H9NO2, Computed Properties of C8H9NO2.
Authors describe the direct coupling of alcs. and amines to a 3-(pyridin-3-yl)propanoic acid ligand coordinated to a Pt(II) to afford ester and amide derivatives Using this approach, a family of trans-Pt(II) compounds with amine ligands bearing long perfluorinated chains was prepared, as these chains potentially endow the complexes with thermoactivatable properties. Related compounds with alkyl chains in place of the perfluorinated chains were also prepared as controls using the same direct coupling method. The stability of the complexes in solution, their reactivity with DNA and proteins, and their antiproliferative activity evaluated in tumorigenic (A2780 and A2780cisR) and nontumorigenic (HEK293) cells at 37 °C and following exposure to elevated temperatures (that mimic the temperatures employed in thermotherapy) were also studied to assess their utility as putative (thermoactivated) anticancer agents.
《Versatile Route to trans-Platinum(II) Complexes via Manipulation of a Coordinated 3-(Pyridin-3-yl)propanoic Acid Ligand》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(3-Pyridinepropionic acid)Computed Properties of C8H9NO2.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem