Recommanded Product: 58656-04-5. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Tricyclohexylphosphonium tetrafluoroborate, is researched, Molecular C18H34BF4P, CAS is 58656-04-5, about Synthesis of Hexahydroindoles by Intramolecular C(sp3)-H Alkenylation: Application to the Synthesis of the Core of Aeruginosins. Author is Sofack-Kreutzer, Julien; Martin, Nicolas; Renaudat, Alice; Jazzar, Rodolphe; Baudoin, Olivier.
Intramol. C(sp3)-H alkenylation of amino-substituted cycloalkenyl bromides, e.g. I (R1 = MeO2C, F3CCO; R2 = Me, Et, cyclohexyl, PhCH2CH2, 4-MeOC6H4CH2OCH2, etc.; R3 = H, Me), provided a unique route to the corresponding hexahydroindoles, e.g. II, with impressive regioselectivity. This approach was successfully used in the synthesis of the octahydroindole core of aeruginosins.
Different reactions of this compound(Tricyclohexylphosphonium tetrafluoroborate)Recommanded Product: 58656-04-5 require different conditions, so the reaction conditions are very important.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem