Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, Journal of Chromatography A called Preparative-scale isoelectric trapping separations in methanol-water mixtures, Author is Shave, Evan; Vigh, Gyula, which mentions a compound: 3724-19-4, SMILESS is OC(=O)CCC1=CC=CN=C1, Molecular C8H9NO2, Quality Control of 3-Pyridinepropionic acid.
The typically low aqueous solubilities of small, hydrophobic organic ampholytic mols. limit the production rates that can be achieved in their isoelec. trapping (IET) separations and call for the use of hydro-organic mixtures as solvents. The compatibility of methanol-water mixtures and poly(ethylene terephthalate) substrate-supported isoelec. polyacrylamide hydrogels, developed for binary IET separations in a Gradiflow BF200IET unit, was studied. The isoelec. polyacrylamide-based hydrogels retained their functional and mech. integrities when the methanol concentration in the hydro-organic solvent mixture was kept at or <25% (volume/volume). The utility of the hydro-organic media was demonstrated in the purification of a hydrophobic ampholytic compound, tech. grade 4-hydroxy-3-(morpholinomethyl) benzoic acid. Production rates ≤7 mg/h were achieved using small, 15 cm2 active surface area isoelec. membranes. The article 《Preparative-scale isoelectric trapping separations in methanol-water mixtures》 also mentions many details about this compound(3724-19-4)Quality Control of 3-Pyridinepropionic acid, you can pay attention to it, because details determine success or failure
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem