Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 16961-25-4, is researched, SMILESS is Cl[Au-](Cl)(Cl)Cl.[H]O[H].[H]O[H].[H]O[H].[H+], Molecular AuCl4H7O3Journal, Evaluation Study, Article, Journal of Agricultural and Food Chemistry called Competitive lateral flow immunoassay relying on Au-SiO2 Janus nanoparticles with an asymmetric structure and function for furazolidone residue monitoring, Author is Su, Lihong; Wang, Lulu; Xu, Jingke; Wang, Zonghan; Yao, Xiaolin; Sun, Jing; Wang, Jianlong; Zhang, Daohong, the main research direction is lateral flow immunoassay gold silica Janus nanoparticle furazolidone; food safety antibiotic residue lateral flow immunoassay; Au−SiO2 Janus nanoparticle; asymmetric structure; furazolidone; lateral flow immunoassay.Name: Hydrogen tetrachloroaurate(III) trihydrate.
Gold nanoparticles (AuNPs) are the most commonly used signal materials in lateral flow immunoassay (LFIA). However, the assay sensitivity of traditional AuNP-based LFIA is usually limited by the incomplete competition between free target analytes and immobilized antigens for the binding of AuNP-labeled antibodies. To unfreeze this limitation, here, asym. Au-SiO2 Janus NPs (about 66 nm) were designed and synthesized. Au-SiO2 Janus NPs can assemble into snowman-like anisotropic structures and combine two different physicochem. properties at their opposite sides, where the AuNP side mainly possesses the antibody conjugating and signal providing functions and the SiO2 side primarily offers the stable function. In virtue of the unique asym. nanostructure, only the AuNP side can interact with target analytes by specific antigen-antibody interactions, which could significantly improve the efficiency of competition. Selecting furazolidone as a model analyte, the immunoassay biosensor showed a limit of detection as low as 0.08 ng/mL, 10-fold decreased than that of the AuNPs-LFIA. Moreover, the Au-SiO2 Janus NP lateral flow immunoassay was well applied in chicken, pork, honey, and beef food samples with visual detection limits of 0.8 ng/g, 0.16 ng/g, 0.4 ng/mL, and 0.16 ng/g, resp. The Au-SiO2 Janus NPs possess the advantages of both materials, which will broaden their applications as a potential alternative in the rapid and sensitive detection of antibiotic residues.
Although many compounds look similar to this compound(16961-25-4)Name: Hydrogen tetrachloroaurate(III) trihydrate, numerous studies have shown that this compound(SMILES:Cl[Au-](Cl)(Cl)Cl.[H]O[H].[H]O[H].[H]O[H].[H+]), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem