Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Tricyclohexylphosphonium tetrafluoroborate, is researched, Molecular C18H34BF4P, CAS is 58656-04-5, about Pd(0)/PR3-Catalyzed Intermolecular Arylation of sp3 C-H Bonds.Synthetic Route of C18H34BF4P.
Pd(0)-catalyzed intermol. arylation of sp3 C-H bonds of pentafluoro anilides has been achieved using aryl iodides and phosphine ligand I. This protocol can be used to arylate a variety of aliphatic carboxylic acid derivatives, including a number of bioactive drug mols. The use of fluorinated aryl iodides also allows for the introduction of fluorine into a mol. of interest.
In addition to the literature in the link below, there is a lot of literature about this compound(Tricyclohexylphosphonium tetrafluoroborate)Synthetic Route of C18H34BF4P, illustrating the importance and wide applicability of this compound(58656-04-5).
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem