The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: tert-Butyl 2-cyanoacetate, is researched, Molecular C7H11NO2, CAS is 1116-98-9, about Microwave-assisted synthesis of 2-aminothiophene derivatives via improved gewald reactions, the main research direction is ethanal oxopropanenitrile sulfur microwave irradiation Gewald reaction; amino thiophene preparation.Application In Synthesis of tert-Butyl 2-cyanoacetate.
In this paper, a new and efficient method was developed to prepare 2-aminothiophene derivatives through improved Gewald reaction. Thirty-one final products were synthesized under microwave radiation for 30 min with 57%-95% isolated yields. All the products could be used as building blocks in drug discovery.
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Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem