The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(2-Bromophenyl)-1H-pyrazole(SMILESS: BrC1=CC=CC=C1N2N=CC=C2,cas:87488-84-4) is researched.Recommanded Product: 70-23-5. The article 《NHC-Copper Mediated Ligand-Directed Radiofluorination of Aryl Halides》 in relation to this compound, is published in Journal of the American Chemical Society. Let’s take a look at the latest research on this compound (cas:87488-84-4).
This report describes an aryl halides e.g., 2-(2-bromophenyl)pyridine radiofluorination reaction in which the C(sp2)-18F bond is formed e.g., 2-(2-fluorophenyl)pyridine-18F via a copper-mediated pathway. Copper N-heterocyclic carbene complexes e.g., I (Ar = 2,6-diisopropylphenyl) serve as mediators for this transformation, using aryl halide substrates with directing groups at the ortho position. This reaction is applied to the radiofluorination of electronically diverse aryl halide derivatives, including the bioactive mols. vismodegib analog II and PH089 III.
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Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem