Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 188637-75-4, is researched, SMILESS is NCC1=NC(Cl)=CC=C1, Molecular C6H7ClN2Journal, Article, Organic Letters called Direct Catalytic Asymmetric α-Allylic Alkylation of Aza-aryl Methylamines by Chiral-Aldehyde-Involved Ternary Catalysis System, Author is Zhu, Fang; Shen, Qi-Wen; Wang, Wen-Zhe; Wu, Zhu-Lian; Cai, Tian; Wen, Wei; Guo, Qi-Xiang, the main research direction is allyl alc ester heteroaryl methylamine chiral aldehyde allylic alkylation; tertiary butyl quinolinyl arylbutenyl carbamate preparation enantioselective.Recommanded Product: 188637-75-4.
A ternary catalytic system comprising a chiral aldehyde, a transition metal, and a Lewis acid was rationally designed for the asym. α-allylic alkylation reaction of aza-aryl methylamines and π-allylmetal electrophiles. Structural diversity chiral amines bearing carbon-carbon double bonds and aza-heterocycles were produced in moderate to good yields with good to excellent enantioselectivities. These products was readily converted into other chiral amines without the loss of enantioselectivity. A reasonable reaction mechanism was proposed to illustrate the stereoselective control results.
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Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem