Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 87488-84-4, is researched, Molecular C9H7BrN2, about Catalyst-Free N-Arylation Using Unactivated Fluorobenzenes, the main research direction is azole indole aromatic substitution fluorine unactivated arene.Category: imidazoles-derivatives.
A valuable and simple novel catalyst-free protocol for the N-arylation of azole and indole derivatives has been described using direct SNAr substitution of fluorine on unactivated benzene derivatives is presented. Reaction conditions have been optimized to effect facile, rapid, versatile, and high-yielding, one-step reactions which tolerate a wide range of substituents on the fluorobenzene and azole/indole derivative, including chloro, bromo, and iodo substituents which result in halogenated N-aryl derivatives This catalyst-free N-arylation reaction is also compatible with metal-catalyzed cross-coupling reactions performed in the same pot simultaneously with, or subsequent to, SNAr substitution of fluorine in fluorobenzene derivatives We predict that these new methods may have wide synthetic utility across organic, medicinal, agricultural, and polymer chem. as well as in materials science applications.
As far as I know, this compound(87488-84-4)Category: imidazoles-derivatives can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem