103057-10-9, name is 4-(Chloromethyl)-1-trityl-1H-imidazole, belongs to imidazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Application In Synthesis of 4-(Chloromethyl)-1-trityl-1H-imidazole
Step H 4-Diethylphosphonomethyl-1-triphenylmethylimidazole The product from Step G is dissolved in acetonitrile and cooled to 0 C. Triethyl phosphite (1 equivalent) and sodium iodide (1 equivalent) were added, and the reaction stirred at room temperature overnight. The reaction is quenched with ammonium chloride, and extracted with ethyl acetate. The organic phase is dried over magnesium sulfate, filtered and concentrated to provide the title compound.
The synthetic route of 103057-10-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Merck & Co., Inc.; US5965578; (1999); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem