Adding a certain compound to certain chemical reactions, such as: 288-32-4, name is 1H-Imidazole, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 288-32-4, Quality Control of 1H-Imidazole
To a stirred solution of imidazole (6.80 g, 100 mmol) in anhydrous dichloromethane (500 mL) was added BrCN (3.70 g, 33 mmol) and stirring was continued at reflux for 30 min. The mixture was cooled to room temperature and concentrated to afford di(imidazole-1-yl)methanimine (4.05 g, 72 %) as a pale yellow solid which was used without further purification.H NMR (DMSO-d6): 10.21 (br s, 1 H, NH), 8.09 (s, 2 H, 2 * CH), 7.57 (s, 2 H, 2 * CH), 7.12 (s, 2 H, 2 * CH).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1H-Imidazole, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; SHIRE, LLC; FRANKLIN, Richard; TYSON, Robert G; GOLDING, Bernard T; WO2012/85586; (2012); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem