Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 930-62-1, name is 2,4-Dimethylimidazole, A new synthetic method of this compound is introduced below., HPLC of Formula: C5H8N2
Preparation 14 Ethyl N-trifluoroacetyl-N-(2-nitro-5-[2,4-dimethylimidazol-1-yl]benzyl)glycinate STR36 A mixture of 2,4-dimethylimidazole (6.25 g), ethyl N-trifluoroacetyl-N-(5-fluoro-2-nitrobenzyl)glycinate (22.0 g) and sodium carbonate (6.62 g) was stirred and heated at 130 for 2 hours. Volatile material was removed from the cooled mixture in vacuo and the residue was partitioned between ethyl acetate (200 cm3) and water (100 cm3). The organic phase was washed with water (2*25 cm3), dried (MgSO4), and evaporated in vacuo to give an oil which was chromatographed on silica (Merck “MK 60.9385” [Trade Mark]) eluding with ethyl acetate:methanol, 1:19. Combination and evaporation of the appropriate fractions gave an oil which crystallized on trituration with ether to afford the title compound, m.p. 172.5-176 (3.1 g). Analysis %: Found: C,50.7; H,4.8; N,12.7; Calculated for C18 H19 F3 N4 O5: C,50.5; H,4.5; N,13.1.
The synthetic route of 930-62-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Pfizer Inc.; US4783467; (1988); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem