Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4856-97-7, name is (1H-Benzoimidazol-2-yl)methanol, This compound has unique chemical properties. The synthetic route is as follows., Safety of (1H-Benzoimidazol-2-yl)methanol
To a three-necked flask was added 1.24 g (6 mmol) of dicyclohexylcarbodiimide, 0.12 g (lmmol) of 4-dimethylaminopyridine, followed by addition of 25 mL of tetrahydrofuran, After stirring and dissolving, Adding 1. 03 g (5 mmol) of 5-nitroindol-3-carboxylic acid, After stirring for half an hour at room temperature, 0.75 g (5 mmol) of 2-light methylbenzimidazole was added and stirred at room temperature for 8 h to stop the reaction. The reaction was filtered, the filtrate was distilled, dried and dissolved in dichloro Methane, standing at room temperature until a large amount of precipitate precipitated, filtered, washed with water, dried in vacuo to give 1.28g (1H-benzimidazol-2-yl) methyl-5-nitro-1H-indole-3-carboxylate in a yield of 76. 19percent.
According to the analysis of related databases, 4856-97-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Qingdao University of Science & Technology; Kang, Congmin; Wang, XinYing; Liu, yizhou; (5 pag.)CN105315262; (2016); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem