Application of 1072-62-4, These common heterocyclic compound, 1072-62-4, name is 2-Ethyl-1H-imidazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
40 mmol of 2-ethylimidazole was dissolved in 20 ml of dimethylsulfoxide (DMS0), and the mixture was milledNa0H80mmol, heated to 60 C, then add 40mmol chloromethyl benzotriazole, 60 C water bath heating lh, cooling to room temperature,Poured into 100g ice water, stirring, precipitation, filtration, precipitation washed 3 times with water to get crude;The crude product was recrystallized from ethyl acetate to give the colored crystals as the ligand 1- (benzotriazole-1-methyl) -1- (2-ethylimidazole).
Statistics shows that 2-Ethyl-1H-imidazole is playing an increasingly important role. we look forward to future research findings about 1072-62-4.
Reference:
Patent; Henan College of Traditional Chinese Medicine; Wang, Xia; Zhang, Chao; Ceng, Dai; Cheng, Di; Song, Ning; Yang, Huai Xia; (11 pag.)(2016);,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem