Synthetic Route of 4856-97-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 4856-97-7, name is (1H-Benzoimidazol-2-yl)methanol belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
1H-benzimidazolyl methanol (2 g, 13.5 mmol) and sodium hydroxide (0.8 g, 20.3 mmol) were dissolved in 20 ml of water.Potassium permanganate (63.9 g, 41 mmol) was added under cooling and stirred at 80 C overnight.After the reaction is completed, the mixture is filtered, and the pH of the filtrate is adjusted to about 3 to precipitate a brown solid.The product was dried to about 1.76. Yield: 78%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (1H-Benzoimidazol-2-yl)methanol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; China Pharmaceutical University; Wang Jinxin; Shang Yanguo; Song Meng; (13 pag.)CN110156708; (2019); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem